Non-coding genetic variation influencing gene expression and splicing is the main source of phenotypic variation within and between species. Here we used genome sequences and gene expression data from diverse human populations to better understand these links, toward more accurate and generalizable models for precision medicine.
Sources of gene expression variation in a globally diverse human cohort
Rajiv McCoy
and Dylan J. Taylor, Surya B. Chhetri, Michael G. Tassia, Arjun Biddanda, Stephanie M. Yan, Genevieve L. Wojcik, Alexis Battle |
Nature, 2024