Sources of gene expression variation in a globally diverse human cohort

Rajiv McCoy and Dylan J. Taylor, Surya B. Chhetri, Michael G. Tassia, Arjun Biddanda, Stephanie M. Yan, Genevieve L. Wojcik, Alexis Battle | Nature, 2024 

Non-coding genetic variation influencing gene expression and splicing is the main source of phenotypic variation within and between species. Here we used genome sequences and gene expression data from diverse human populations to better understand these links, toward more accurate and generalizable models for precision medicine.