Microbiome-derived acidity protects against microbial invasion in Drosophila

Nichole Broderick and Alexander J. Barron, Sneha Agrawal, Danielle N. A. Lesperance, Jeremy Doucette, Sthefacy Calle | Cell Reports, 2024 

Barron et al. demonstrate that interactions between members of the Drosophila microbiome influence the pH of the fly environment. Acidification by the microbiome, primarily through production of lactic acid by bacteria, protects the host from invasive microbes.